The International Cooperation on Harmonisation of Technical Requirements for Registration of Veterinary Medicinal Products (VICH) has announced the launch of public consultations on the revision of existing guidance. The document addresses the validation of analytical methods applied in conducting studies of residual content of veterinary drugs in animal-derived products obtained from farm animals. Studies of residual drug content are necessary to assess how quickly and in what concentrations medicinal substances and their metabolites are eliminated from animal tissues after treatment cessation. This data is used in establishing withdrawal periods — intervals during which meat, milk, eggs, and other animal-derived products cannot enter the human food chain due to possible residual drug substance content. The revision of the guidance aims to update requirements for the validation of analytical methods, which should improve the accuracy and reliability of data obtained during studies. The updating of methodological recommendations is important for manufacturers of veterinary drugs, regulatory authorities, and laboratories engaged in quality control of livestock products. The consultation period is open until April 25, 2027, providing interested parties — including pharmaceutical companies, the scientific community, regulators, and veterinary specialists — with an extended timeframe to review the proposed changes and submit their comments and suggestions. VICH brings together regulatory authorities and representatives of the veterinary pharmaceutical industry from various countries worldwide with the aim of harmonizing technical requirements for the registration of medicinal products for animals, which facilitates the simplification of international trade in such products while maintaining high safety standards for animals and humans.